AQUACEL® Ag dressing for surgical wounds
AQUACEL® Ag dressing does more than just provide antimicrobial activity.
*Artist's interpretation
AQUACEL® Ag Hydrofiber® Dressing with Silver, Sterile
is indicated for moderate to high exuding wounds which are infected or at risk of infection.
Because it is the only antimicrobial dressing that incorporates Hydrofiber® Technology, it:
- Releases ionic silver in a controlleda manner as wound exudate is absorbed into the dressing1,2
- May help protect peri-wound skin by helping reduce the risk of macerationb,3,4
- May help minimise cross-infection during dressing removalb,5
- Is soft and conformable6
- Supports wound healing by providing a moist wound healing environment7
AQUACEL®Ag dressing provides rapid and sustained antimicrobial activity in vitro.1,2,8
As demonstrated in in vitro testing, AQUACEL®Ag dressing provides sustained antimicrobial activity for up to 7 days.2
SCHEMATIC ILLUSTRATION OF SEQUESTRATION OF BACTERIA BY HYDROFIBER® TECHNOLOGY
*Artist's interpretation
CLINICAL STUDY RESULTS
Jurczak, et al. 2007 [+]
In a randomized trial of 67 patients, comparing AQUACEL®Ag dressing with povidone-iodine gauze in the management of open surgical and traumatic wounds:8
- "At final evaluation,...(AQUACEL®Ag dressing )...was significantly better than povidone-iodine gauze for overall ability to manage pain (P<0.001)"
- AQUACEL®Ag dressing was significantly better than povidone-iodine gauze in terms of wound trauma on dressing removal (P<0.001) and ease of use (P<0.001)
- At study completion 23% of subjects managed with AQUACEL®Ag dressing had healed versus 9% for povidone-iodine gauze, although statistical significance was not achieved.
AQUACEL®Ag dressing was significantly better than povidone-iodine gauze for the management of exudate (P<0.001)
References [+]
- Bowler PG, Cochrane CA. Progression toward healing: wound infection and the role of an advanced silver-containing Hydrofiber® dressing. Ostomy Wound Manage. 2003:49(8)(suppl):S 2-S5.
- Jones SA, Bowler PG, Walker M, Parsons D. Controlling wound bioburden with a novel silver-containing Hydrofiber® dressing. Wound Repair Regen. 2004;12:288-294.
- Coutts P, Sibbald RG. The effect of a silver-containing Hydrofiber dressing on superficial wound bed and bacterial balance of chronic wounds. Int Wound J. 2005;2(4):348-356.
- Robinson BJ. The use of a hydrofibre dressing in wound management. J Wound Care. 2000;9(1):32-34.
- Walker M, Hobot JA, Newman GR, Bowler PG. Scanning electron microscopic examination of bacterial immobilisation in a carboxymethylcellulose (Aquacel) and alginate dressings. Biomaterials. 2003;24(5):883-890.
- Jones S, Bowler PG, Walker M. Antimicrobial activity of silver-containing dressings is influenced by dressing conformability with a wound surface. Wounds. 2005;17(9):263-270.
- AQUACEL® Ag Hydrofiber® Wound Dressing [CE Mark package insert ConvaTec 1137338]. Deeside, UK: ConvaTec Limited 2002
- Jurczak F, Dugre T, Johnstone A, Offori T, Vujovic Z, Hollander D. Randomised clinical trial of Hydrofiber dressing with silver versus povidone-iodine gauze in the management of open surgical and traumatic wounds. Int Wound J 2007; 4(1): 66-76.
Notes [+]
- The amount of silver released is controlled by the maximum amount of silver that can get into solution
- In in vitro testing for AQUACEL® dressing, which is of the same construction as AQUACEL Ag® dressing with the exception of the addition of ionic silver